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Djufaston during pregnancy
The problem of miscarriage was always relevant. There is a natural mechanism that helps prevent miscarriage - it increased production by the body of the female hormone progesterone. But sometimes it is not enough progesterone is produced.
The natural mechanism to prevent miscarriage
Miscarriage is called its spontaneous abortion or miscarriage. Sometimes it happens by accident, after stress, heavy physical exertion or some diseases (especially after infectious and inflammatory diseases of female genital organs), but in some cases the miscarriage becomes habitual. In this case we speak about violation of the natural mechanism for the prevention of miscarriage.
A natural mechanism that helps nurturing pregnancy is increased secretion of the female hormone progesterone, warning muscle contractions of the uterus. This hormone begins to produce the second half of the menstrual cycle
The menstrual cycle - that occurs in different phases?
the corpus luteum of the ovaries and in the case of pregnancy the amount it increases sharply as the corpus luteum grows and becomes the corpus luteum of menstruation in the corpus luteum of pregnancy. This occurs under the influence of another hormone - human chorionic gonadotropin (hCG). HCG begins to stand out shell of the embryo in the place of its attachment to the uterine wall after the introduction of a fertilized egg in the uterus of a week after fertilization. The main objective of hCG is the stimulation of progesterone secretion by the corpus luteum.
In addition to direct effects on the muscles of the uterus, progesterone has an effect on the immune system of women. Under the influence of progesterone immune cells of pregnant women (T-lymphocyte) produce progesterone-induced blocking factor (PIBF), which provides the proper course of pregnancy
Pregnancy - nine awaited months
, Rebuilding the immune system of a pregnant woman, allowing to carry and give birth to a child. When the immune cells produce little pregnant PIBF, her immune system rejects the fertilized egg, that is, there is a spontaneous abortion.
Lack of progesterone is particularly dangerous in the first and second trimesters of pregnancy (the first 24 weeks).
In this case, there is an increased contractility of the muscles of the uterus (uterine hypertonus), which leads to miscarriage
Miscarriage - is more common than you think
. But today, obstetricians have learned to cope with such problems.
The mechanism of action duphaston during pregnancy
Djufaston is a synthetic analogue of natural progesterone, which has all the properties of natural progesterone. Furthermore, unlike the latter, may be taken orally djufaston whereas natural progesterone administered only intramuscularly. And since this oil solutions, they often cause early suppurative process.
Besides the usual action of progesterone (suppression of uterine muscle contraction and expansion of its muscle fibers, stimulating the production of PIBF), djufaston helps other positive effects of female sex hormones - estrogen on the metabolism of fat in the body of the mother.
This djufaston does not have any negative impact on the mother and child, including the liver and carbohydrate metabolism, therefore has virtually no contraindications.
Obstetricians prescribe djufaston under laboratory control (determined by the amount of progesterone in Croke mother) in the first 24 weeks of pregnancy (I and II trimesters). At the end of this period djufaston gradually abolish - the sudden cancellation of the drug can cause an abortion.
Djufaston used both during pregnancy and in certain types of menstrual disorders (its second half), which lead to the impossibility of pregnancy.
Efficiency duphaston during pregnancy
Djufaston - a drug that has a high efficiency. At his regular admission to the first weeks of pregnancy, even with the already established habitual miscarriage, it is possible to communicate and give birth to a healthy baby. Duphaston can help even in the case where abortion has already begun (in the initial stage), as dramatic suppression of muscle contractions of the uterus and stimulates the immune system helps to prevent the removal of the ovum and maintain a pregnancy.
Today, synthetic analogs of progesterone (including djufaston) very often prescribed in the early stages of pregnancy to help prevent miscarriage in women even with the already established tendency to miscarriage.
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