Djufaston often prescribed for endometriosis in the initial stages of the disease or with small lesions. In this case, djufaston can actively suppress the growth of the mucous membrane of the uterus (endometrium), thereby preventing the spread of the pathological process.
What happens in women with endometriosis
Endometriosis is always a consequence of increased endometrial growths (proliferation) under the influence of a large number of female sex hormone estrogen. Progesterone while not enough to suppress the process of proliferation and transfer phase in secretory phase characteristic of the second half of the normal menstrual cycle.
Therefore rejection of the endometrium occurs at reducing the amount of estrogen in the body, and this rate can stay long at the high level or the decrease, then increase, thereby increasing the length of the menstrual cycle. Start of menstruation associated with necrosis and rejection of individual sections of the endometrium, which results in prolonged heavy menstrual bleeding. It is also possible intermenstrual bleeding.
During menstruation, endometriosis occurs cast sections of the endometrium and its individual cells in the muscle layer of the uterus, fallopian tubes, ovaries, cervix and vaginal wall. In order for these cells took root in tissues foreign to them, such a condition is necessary as reduced immunity, immunity in the normal endometrial cells are destroyed immediately.
Once in other tissues, endometrial cells begin to multiply, forming areas of tissue that are identical to the inner membrane of the uterus. This fabric is subject to cyclic changes as the endometrium of the uterus, i.e. the first half of the menstrual cycle, it grows under the influence of estrogen, and then torn away, causing or bleeding or hematoma in the area of the body where there are areas of endometriosis. Hematoma germinate connective tissue, forming areas of sclerosis.
How does endometriosis djufaston
Djufaston - a synthetic analogue of progesterone. Endometriosis it selectively suppresses endometrial growth not only in the uterus, but also in the foci of endometriosis. This leads to the fact that the regulated menstrual cycle, decrease of blood loss during menstruation and intermenstrual bleeding, and therefore, decrease pain and - the main symptom of endometriosis.
The main advantage is its duphaston mild effects on the reproductive system of women. This drug does not suppress ovulation, therefore, a woman suffering from endometriosis and receiving in connection with this djufaston
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May become pregnant
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. Duphaston has no negative impact on the process of conception
Conception - as the emerging life
and a fertilized egg, so it is often continue to take during pregnancy. The very same process of pregnancy has a positive effect on endometriosis, since it removes the reason for his progression - the expansion and rejection of the endometrium.
But djufaston - a drug with a mild and not too intense effect of suppressing the proliferation of the endometrium, so it is prescribed in the initial stages of the disease and small foci of endometriosis. Very often djufaston prescribed to women with endometriosis who are planning a pregnancy.
For the treatment of large or multiple foci of endometriosis used other drugs, as well as surgical treatment.
As prescribed djufaston endometriosis
Experts note that the treatment of endometriosis requires an individual approach. Djufaston endometriosis is also assigned to the individual dosages of the different duration of the course.
Manufacturers of the drug (the American pharmaceutical company Abbott) recommend taking it with endometriosis from the fifth to the twenty-fifth day of the menstrual cycle (if cycle in twenty-eight days) two or three times a day from six months to nine months.
Do duphaston contraindications and side effects
Contraindications for the purpose duphaston endometriosis is individual intolerance of components woman's body. In addition, djufaston shall not apply if during pregnancy a woman has been the phenomenon of jaundice.
Side effects may cause headaches, including migraines as, and breakthrough bleeding. The last side effect can be eliminated by increasing the daily dose duphaston.
Cases of drug overdose has not yet been reported. But if a woman accidentally took a lot of pills at once this drug, you need to wash the stomach.
Duphaston can help in endometriosis, but only if a woman takes it on prescription.
Galina Romanenko
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