Enzymes

Papain

Papain enzyme contained in papaya, destroys intercellular communication. Papain is used in the treatment of hypertrophic scars and to exfoliate stratum corneum. Papain has a keratolytic effect.

Enzymes recover deoxyribonucleic acid (DNA)

Cyclobutane-pyrimidine dimers formed by UV light in the spectrum (UV-B) in the DNA of epidermal cells, are harmful to humans and cause cell mutation and immunosuppression that provokes fotokantserogenez. Lotions containing enzymes repair DNA which have been isolated from bacterial lysates and photolyase-containing liposomes have demonstrated a positive effect in prekantserogennyh and carcinogenic processes in the skin. When enzyme vosstanavleniju DNA delivered into the cell, there is the effect of accelerated recovery of DNA damaged by ultraviolet light in human cells.

It is found that the application of enzymes repair DNA on photodamaged skin reduces rates of actinic keratosis and basal cell epithelioma, within one year of treatment. Topical application of photolyase-containing liposomes by 40-45% reduces the formation of harmful dimers formed by ultraviolet radiation in the skin.

These dimers are completely restored, preventing UV-induced immunosuppression, accompanying solar erythema and burns. Studies have shown that topical application of enzymes that repair DNA, could be effective in the recovery of pathogenic dimers, restore immunoprotektornye properties and reduce the risk of fotokantserogeneza.

Epidermal growth factor

Epidermal growth factor (EGF) is contained in plasma, sweat glands, urine, saliva and semen. When the epidermal growth factor binds to the epidermal growth factor, which stimulates growth and differentiation of the epidermis. This property has been used in the treatment of burns, cuts of the skin to re-epithelialization.

Transformational Growth Factor

Transformational growth factor (TGF) stimulates the growth of normal skin cells and restore them. Transformational growth factor has a positive regulatory effect on the accumulation of extracellular proteins (procollagen, collagen, elastin). Transformational growth factor regulates fibroplastic processes (restoration of the skin) and angiogenesis (growth of new blood cells) and promotes the healing process.

Hormones

It is believed that hormonal creams are the most effective means of stopping or slowing down the aging process Internal and external aging: it is necessary to think in advance As reduced skin tone and elasticity. Scientific evidence podtkreplyayuschie this opinion have not yet been published.

Estrogens

Estrogen - a female sex hormones: estrol, estrone. Studies have shown that estrogens have an anti-aging effect. For example, one study showed that the application of 0, 01% estradtola and 0, 3% estriol increases elasticity, skin elasticity, reduces wrinkles and pore size. Immunohistochemical analysis significantly increases the content of collagen type III collagen fibers and the end of treatment. Furthermore, systemic side effects were observed. However, additional clinical studies for wider use them as anti-aging ingredients.

Progesterone is

Creams with progesterone have shown the ability to restore damaged as a result of the aging process collagen molecules and restore immunity. Some manufacturers claim that creams containing progesterone have a positive effect on acne, psoriasis, rosacea, seborrhea Seborrhea - treatment is not complicated, but mandatory   and keratosis. Other manufacturers claim that progesterone creams to help with the correction of premenstrual syndrome (PMS), menopause and osteoporosis. But these claims are not supported by sufficient scientific justification.

Testosterone

Topical application is quickly becoming the method of choice for the treatment of testosterone. Theoretically, the topical application of testosterone, bypassing the gastrointestinal tract and the liver, does not cause further undesirable increase in estrogen levels in the blood. Manufacturers claim that testosterone creams have numerous beneficial properties: improve memory, have antidepressant effect, increases resistance to stress and the ability to treat the symptoms associated with hypogonadism (increased fat tissue, reduced muscle mass). Recent studies show that daily application of testosterone to the skin recovers its level in the blood at hypogonadism in men.

Growth hormone

HGH (growth hormone, GH) and its mediator insulin-like growth factor-1 (IGF-1), are responsible for many of the mechanisms of growth, development, immunity and metabolism. Growth hormone produced and secreted by the anterior pituitary gland and is characterized by a pulsed release signal under the influence of the hypothalamus. Growth hormone has anabolic effects on the entire body, promoting the growth of tissue, bones and muscles. Studies have shown that aging is accompanied by a reduction in growth hormone levels in the body, thereby reducing the body weight, fat stores, immunity and overall energy level.

Botulinum exotoxin A

Botulinum exotoxin A - a neurotoxin produced by the bacterium Clostridium botulinum. This toxin is used in medicine and aesthetic medicine for correcting a wide range of conditions. The aesthetic medicine is used to prevent facial wrinkles. As a relatively simple and effective non-surgical method, injection of botulinum A exotoxin allow you to adjust "crow's feet" and wrinkles in the upper third of the face. This causes temporary chemical denervation of facial muscles. Additionally, botulinum exotoxin A can be used for blocking the sympathetic innervation of sweat glands to correct hyperhidrosis in the armpits, palms and feet.

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