Djufaston - the drug in tablet form for oral administration, which is used to treat a number of diseases and disorders caused by too low levels of the hormone progesterone. The active substance duphaston - dydrogesterone, a synthetic hormone progestin, progesterone deficiency compensation. Djufaston was first synthesized in the early shesyatidesyatyh years and since then has been used successfully in gynecology for effective treatment and prevention of various diseases.

How does djufaston

Progesterone is necessary for normal menstrual cycle and pregnancy. Peak levels of the hormone progesterone after ovulation up to when the body starts preparing women for pregnancy - in particular, it is progesterone causes thickening of the lining of the uterus. If pregnancy does not occur, and the fertilized egg is not attached to the uterus wall, the progesterone level at the end of the menstrual cycle decreases, which leads to delamination of the endometrium and the start of menstruation. If pregnancy occurs, progesterone levels in women remains high, which ensures normal process of implantation of the egg and the course of pregnancy.

Didrogesteron molecular structure and pharmacokinetics similar to progesterone, and therefore has no harmful effects on the body.

In addition, djufaston useful in hormone replacement therapy for menopause and during pregnancy, because it helps reduce the risk of a possible miscarriage.

Benefits

• Because of the similarity to endogenous progesterone does not cause the side effects typical of other progestogens
• Readily absorbed in the body, it has no effect on the gastrointestinal tract
• It does not affect the processes occurring in the course of the menstrual cycle - including ovulation
• Reduces contractile ability of the uterus, thereby minimizing the risk of miscarriage
• It suppresses the process of cell division of the endometrium, thus contributing to the treatment of endometriosis
• It can be used for treating various diseases and disorders, and for the prevention of
• The absence of teratogenic effects - djufaston has no effect on fetal development and therefore is safe when taken in pregnancy

Djufaston: indications for admission

Duphaston is shown to receive under certain menstrual cycle (for example, irregular menstruation, dysmenorrhea), as well as diseases caused by deficiency of the hormone progesterone, and the treatment of infertility. Duphaston is recommended to take in the following cases:

• During the menstrual cycle: irregular cycle, dysmenorrhea (absence of menstruation)
• When pronounced symptoms of premenstrual syndrome
• At the risk of miscarriage
• In endometriosis
• When infertility provoked by hormonal imbalance
• When uterine bleeding of various origin

Side effects from the drug are very few - only in rare cases after taking duphaston may experience vaginal bleeding, nausea, headache Headache Bloating Bloating - when you need to go to the doctor? . Djufaston contraindicated only when dydrogesterone allergy to progesterone, or other derivatives.

Recommended dosage

Accept djufaston necessary either continuously or during certain days of the menstrual cycle - in accordance with instructions of the doctor. The duration of treatment depends on the severity of the disease may be up to several months.

• To suppress the symptoms of premenstrual cycle: Ten milligrams twice daily from the time of ovulation to the end of the cycle (the eleventh to twenty-fifth day of the menstrual cycle)
• To normalize the menstrual cycle periodicity: Ten milligrams twice a day of the eleventh to the twenty-fifth day of the menstrual cycle (to start a course of treatment is necessary after the last menstrual period)
• When dysmenorrhea: five to ten milligrams of the drug twice a day from the fifth to the twenty-fifth day of the menstrual cycle
• Endometriosis: Ten milligrams of the drug two or three times a day
• To prevent miscarriage: an initial dose duphaston - forty milligrams, then - ten milligrams every eight hours until symptoms disappear
• For the treatment of infertility: Ten milligrams duphaston twice a day from the eleventh to the twenty-fifth day of the menstrual cycle

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