What unites chronic thyroid disease

Chronic processes are varied, most often among these forms of the disease are faced with autoimmune thyroiditis nature. It contributes to the increased incidence of immune stimulation by artificial antigen to which the human body has not previously contacted. Autoimmune diseases occur with clinical hypofunction or hyperthyroidism, so conditionally distinguish several clinical variants.

A distinctive feature is the gradual emergence of symptoms. In the course of an autoimmune disease is the development of destructive processes in a certain proportion of cancer, but preserved tissue to compensate for violations. In the early stages of the disease are not observed gland dysfunction. The development of functional changes occur with the growth of destructive processes. In this case, patients show signs of hyperthyroidism (due to excess intake of hormone in the blood, which was previously synthesized) or hypothyroidism Hypothyroidism .

The end result of an autoimmune process is hypothyroidism with all the symptoms characteristic of the disease in the classic representation. At the initial stage of the disease is observed hyperthyroid phase, which lasts for several months. This feature allows the physician to diagnose correctly. When it comes to toxic goiter, the thyrotoxicosis Hyperthyroidism: problems with the thyroid gland   there will be long-term, short-term periods of change will not be observed. Chronic autoimmune processes are not pronounced eye symptoms. It is very rare to find endocrine ophthalmopathy, even with the development of its symptoms are not severe, they differ mild manifestations. Unlike ophthalmopathy in toxic goiter thyroiditis observed spontaneous remission.

One of the current problems is considered to be a combination of endocrine autoimmune thyroid disease and pregnancy. Such forms include changes in the gland in the postpartum period. Symptoms appear in women who have not previously had thyroid pathology. Objectively iron increases to level II or III, wherein it is painless. The signs of hypothyroid state include general weakness and fatigue, increased sensitivity to cold, constipation. With timely appointment of medical correction comes a significant improvement in overall condition.

The value of antithyroid antibodies

Confirmation of the presence of an autoimmune disease is found in the blood of classical antithyroid antibodies. They can be found in almost 90% of cases and in a very high concentration. Unable to confirm the existence of the mutual relationship between the severity of clinical symptoms of thyroiditis and antibody titer. Previously it was thought that the diagnostic criterion thyroiditis is to detect in the blood of antibodies to thyroglobulin. Thanks to the advances of modern medicine in this statement Now scientists refute. Who is able to establish that you can detect similar changes in the varieties of cancer, with toxic goiter. Conducting research on the detection of antibodies to thyroglobulin allows you to diagnose different vnetireoidnymi changes, so it is referred to as auxiliary methods.

The most reliable method of diagnosis is a needle biopsy. With this method it is possible to confirm the nature of the disease, but it also can not be considered final by confirming the diagnosis. More help from the biopsy is the ability to confirm or exclude the presence of specific diseases which include tuberculosis, syphilis and others. Only a comprehensive approach, taking into account in the evaluation of the clinical picture and the results of the survey fails to diagnose a chronic autoimmune process. If the diagnosis is established early in the disease course and conducted active therapeutic measures, the patient can be considered a favorable prognosis. There is a risk of development of malignant processes in chronic thyroiditis, but the data are contradictory. In most cases, you can identify the combination with adenocarcinoma or lymphosarcomas.

Early diagnosis of thyroid diseases contribute to the radioimmunoassay detection of hormones in the blood. Not only evaluates the level of thyroid hormones, but also the central hormone (TSH). For the diagnosis of hypothyroid condition is important to the value of TSH. Violations of the cancer are also supported on the basis of various hormonal tests (for example, after stimulation with intravenous administration tireoliberina conduct performance measurement of hormones, their deviations).

Despite the favorable outcome of the disease, patients ability to work in the period after recovery is dependent on the degree of compensation of hypothyroidism. After suffering an autoimmune disease patients should be monitored constantly, they put on a clinical account. ALWAYS dynamic laboratory testing, drug treatment is appointed at deviations from normal performance level of hormones.

Marina Solovyov

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