Today, there are not so many effective drugs to reduce body weight. Most often under the guise of preparations, we are trying to sell a variety of biologically active food additives and well even if they do not contain harmful substances for the organism. Xenical - exclusion, it is indeed an effective drug, manufactured by a reliable pharmaceutical company.

The mechanism of action of Xenical

Xenical (international non-proprietary name - Orlistat) refers to a group of drugs that suppress the action of lipases (enzymes that break down fats) of the gastrointestinal tract, long-acting. Active substance Xenical joins the lipase in the lumen of the stomach and small intestine, resulting lipase loses its activity and can not break down fats. Since uncleaved fat is not absorbed, the reduced number of calories entering the body, and thus the weight of the body. That is, the therapeutic effect of Xenical provided locally in the gastrointestinal tract, substantially without absorption into the bloodstream. Received food fats almost entirely excreted in the faeces unchanged.

Using long Xenical can control body weight, maintaining it at a desired level. Therefore, it is used in various diseases, which are accompanied by obesity, especially if obesity contributes to the worsening of the disease (eg, diabetes, atherosclerosis Atherosclerosis - when problems with blood vessels , Hypertension, etc.).

We investigated the possibility and the suction side of Xenical in the blood. It has been found that a tiny fraction of absorbed dose, which practically has no any influence on the organism. The drug also accumulates in the body.

After receiving the drug inside the capsule of Xenical takes effect within one-two days. The effect lasts two or three days.

Indications and contraindications

Admission Xenical is indicated for:

• obesity, especially to patients at risk for diabetes Diabetes   and atherosclerosis; receiving Xenical it is recommended to combine with reduced calorie diet;
• when combined type 2 diabetes are overweight; in this case used together with Xenical hypoglycemic agents or with moderate calorie diet.

Do not take Xenical if:

• a person suffers a chronic malabsorption syndrome;
• violation of motor activity of the biliary tract, which leads to stagnation in this area;
• have individual intolerance of components.

Clinical studies have not been performed, so the drug is not recommended:

• at the age of 18;
• Pregnancy and breast-feeding the child.

How to take Xenical

Xenical take one capsule during or after (but not later than one hour) meal (based meals three times a day). Taking the capsules can be omitted if the food does not contain fat. It proved that taking high doses of the drug does not increase its therapeutic effects. The dose does not change depending on the condition of the patient.

Since Xenical displays unmodified fats, it may interfere with the absorption of fat-soluble vitamins Vitamins for everyone   (A, D, E, K and beta-carotene), so it is recommended to combine it with the reception of vitamin-mineral complexes, which have to take two hours after taking Xenical.

In addition, when receiving Xenical person must obtain food having a low fat, many fruits and vegetables.

Possible side effects of Xenical

Major side effects while taking Xenical due to the fact that the intestines are not absorbed fats, however the following phenomena may occur:

• oily discharge from the rectum;
• involuntary discharge of gas with a quantity of feces;
• pronounced urge to defecate, frequent bowel movements;
• fecal incontinence;
• pain and discomfort in the rectal area.

In order to prevent the emergence of such phenomena, the patient should eat food containing a reduced amount of fat, which at the same time prepares the patient for further (without Xenical) reduction of a fatty meal. In addition, you may experience side effects associated with disorders of fat metabolism:

• loss of teeth and gums;
• decreased immunity (frequent colds, including viral infections, urinary tract infection);
• menstrual irregularities;
• headaches, anxiety, weakness.

Very rarely allergic reactions occur. Diabetic patients may sharp decline in blood sugar due to improved carbohydrate metabolism.

Xenical overdose have been identified.

Xenical - highly effective drug designed for long-term treatment of obese patients under medical supervision. He produced a reliable Swiss pharmaceutical company "F. Hoffmann-La Roche. "

Galina Romanenko

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