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 depigmenting agents Cosmetics

Depigmenting agents

Hyperpigmentation - a very common and potentially dangerous condition that occurs in a large part of the population, so dermatologists must understand the clarifying agent in the composition of cosmetics and corrective concealer. The combination of medical cosmetics with sunscreen Sunscreen: summer trends  Sunscreen: summer trends
   It is often the most effective treatment.

Hyperpigmentation - the result of increasing the amount of melanin Which foods contain melanin - skin care  Which foods contain melanin - skin care
   in the epidermis and / or dermis. These pigmentation changes may be caused by two pathophysiological processes: melanotsitozom (increase in the number of melanocytes) and melanosis (increased amount of melanin). Depigmentation agents work best when melanosis or melanotsitoz limited to the epidermis. It is also used for depigmentation chemical peels.

Patients with I-III skin type Fitzpatrick recommended local lighting and depigmentation when hormonally induced melasma and post-inflammatory hyperpigmentation, acne and caused injuries. Patients with IV-VI skin type Fitzpatrick may also need lechechenie pigmentary changes around the eyes, in areas prone to diaper rash after dermatitis and acne, and mechanical damage. The reference dermatological skin lightening hydroquinone was traditionally considered as long as their safety has been questioned. Today, for this purpose, a wide range of alternative depigmenting agents such as retinoids Retinoids against skin aging: means of wrinkles  Retinoids against skin aging: means of wrinkles
 , Mekvinol, azelaic acid, arbutin, kojic acid, aleosin, licorice extract, ascorbic acid, soy protein and N-acetyl glucosamine.

Depigmenting agents can be divided into several groups:

  • Phenolic compounds:
  • Hydroquinone;
  • Monobenzilefir hydroquinone;
  • 4-methoxyphenol;
  • 4 izopropilkatehol;
  • 4-hydroxyanisole;
  • N-acetyl-4-S-tsisteaminilfenol.

Non-phenolic compounds:

  • Corticosteroids;
  • Tretinoin;
  • Azelaic acid;
  • N-acetylcysteine;
  • L-ascorbyl-2-phosphate;
  • Kojic acid.

Combined agents:

  • Kligman formula;
  • Formula Pataca;
  • Formula Vestergofa.

 Medical cosmetics - to solve skin problems - depigmentation agents

N-acetyl-4-S-tsisteaminilfenol

Phenol thioester, N-acetyl-4-S-tsisteaminilfenol represents a new type of bleaching (depigmenting) agent. It promises to be more stable and less irritating to the skin than hydroquinone, and isotropic cells, melanocytes. Monophenolic component tert-butyl-4-hydroxyanisole (mekvinol) has been studied in connection with the treatment of solar lentigines and associate them hyperpigmentation. Topical combined means comprise 2% of 4-hydroxyanisole and 0 01% solution of tretinoin (Solage) are well tolerated and exhibit improved efficiency.

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