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Depilatories
Depilatory agents
Traditional chemical depilatory agents contained in gels, creams, lotions, aerosols, - a thioglycolic acid salt (sodium or calcium thioglycolate), which have been patented in the 1930s as a means of dehairing cattle hides.
Thioglycollate with depilatory action is based on the hydrolysis and breaking of disulfide bonds in hair keratin
Hair: structure, characteristics of growth and development
, Causing the hair to break and can be separated from the skin.
Pinacidil, P-1075, and nicorandil kromakalim
The opening of intracellular potassium channels - a common mechanism of action of some antihypertensive drugs, which include Minoxidil, a substance that stimulates hair growth. Recent studies show that the substances potassium channel openers (PCO), also affect hair growth. Correlation studies show that the number of PCO, including pinacidil, P-1075 (active analogue pinacidil) kromakalim nicorandil and stimulate hair growth.
Cysteine and arginine
Proteins with a high sulfur content - are proteins rich in cysteine that are synthesized during the differentiation of matrix cells and hair, together with intermediate microfilaments hair keratin hair fiber form. Trihohialin (THH) - the main structural protein of cell membrane and the inner core of the hair follicle and, to a lesser extent, other specialized epithelium formed by converting arginine to citrulline.
With Palmetto (Serenoa repens)
With Palmetto has a local action at the site of the actual hormone binding to receptors in cells. Substance stops or at least reduces binding to androgen receptors. It is also locally inhibits 5-alpha reductase and 3-ketosteroid reductase enzymes involved in the conversion of testosterone to the more potent dihydrotestosterone. Green tea is associated with increased binding globulin sex hormones (SHBG). Testosterone is associated with SHBG, is biologically inactive and unable to bind to androgen receptors or transformed to DHT. Green tea also may affect the enzyme alpha reductase type I 5.
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